Category Archives: Toxicology

LAMOTRIGINE AND KETAMINE

The other day, I was called to the ED to assist in chemically controlling one of our psychiatric usual suspects who had been admitted with her customary friday night OD. This time she had ingested an unknown amount of the … Continue reading

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CORONARY CAPSAICIN CONUNDRUM

Weird case report in Int J Emerg Med. Apparently people use cayenne pills for weight-loss. (Me, I maintain navy-seal fitness, so I wouldn’t know).  One of the active components in cayenne pepper pills is Capsaicin, a substance that increases energy expenditure … Continue reading

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SAY HELLO TO MY LITTLE FRIEND, THE LIPID-SINK EFFECT

We know intravenous injection of lipid emulsion is an effective antidote of some overdoses of lipid-soluble drugs like the local anaesthetics, beta-antagonists, calcium channel blockers and antidepressants. I never thought of it being used as an antidote in cocaine toxicity.

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