Category Archives: Infectious diseases

EGDT IS DEAD, LONG LIVE EGDT

And so the EGDT trilogy is complete. The results of the ProMISe trial was published, after we’ve recently had the results from the ARISE and ProCESS trials. They all compared EGDT (Early Goal-Directed Therapy) to “standard care”. And they were … Continue reading

Posted in Emergency Medicine, Infectious diseases, Intensive Care | 5 Comments

THE MOTTLING SCORE

Several methods have been developed for identifying and quantifying microcirculatory dysfunction in septic shock. We can measure buccal, sublingual and subcutaneous microcirculatory CO2-levels. Near infrared spectroscopy (NIRS) measures microcirculatory hemoglobin saturation. Sidestream dark field (SDF) imaging directly visualises the microcirculation. … Continue reading

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SEPSIS PROGRESS

The PROCESS and SEPSISPAM studies were serious blows to protocol EGD therapy in sepsis. With all the other dead ends we pursued (activated protein C, colloids, intensive insulin therapy, cortisone and what not) it is tempting to think that little … Continue reading

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BETA BLOCKERS MIGHT GIVE ADVANTAGE IN SEPSIS

A study in Crit Care Med suggests sepsis patients that are on β-blockers might have a survival advantage over patients that are not on β-blockers. Despite β-blocked patients having more prior cardiac disease, hospitalisations and cardiac risk factors.

Posted in Emergency Medicine, Infectious diseases, Intensive Care | 2 Comments

DENGUE

In a recent issue of annals of emergency medicine a french group in Martinique has reviewed the symtoms of patients with dengue fever on arrival to the ED. It seems to be endemic over there so the authors can present … Continue reading

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