THROMBOLYSIS FOR STROKE? THE IST-3 TRIAL

I am probably the last person on earth to read the IST-3 trial. In short, the authors’ conclusion of ´strong support for thrombolytics in stroke´ was pisspreik somewhat controversial and generated some discussion.

Read this excellent post about the IST-3 trial and thrombolysis in stroke in general on ED Trauma Critical Care. There is also a good list of links, resources and comments on the IST-3 trial. Among the comments:

“…In a secondary analysis (which means – since we found no significant benefit, this is how we manipulated the data to make it appear so)….”

Awesome.

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One Response to THROMBOLYSIS FOR STROKE? THE IST-3 TRIAL

  1. Thomas D says:

    The post on the EDTCC blog is excellent! One has to wonder if the investigators’ often desperate want for positive and significant results for their big trials are as dangerous and destructive for evidence based medicine as coercion by pharmaceutical companies.

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